Onconova Therapeutics, Inc., founded in 1998, is a private biopharmaceutical company located in Newtown, PA and Lawrenceville, NJ.
The Company is focused on targeting cancer and protecting healthy cells. Based on a proprietary medicinal chemistry library of over 125 novel chemotypes, Onconova has discovered and optimized a number of small molecule therapeutics aimed at novel molecular and biological targets.
The Company is developing targeted anti-cancer therapeutics by taking advantage of increased understanding of how normal cells change to become cancerous and exploiting differences in cell cycle regulation of normal versus cancer cells.
Onconova is using its proprietary chemistry platform and expertise in molecular and cell biology and genomics to develop potent agents to treat effects of radiation injury.
The Company's current discovery efforts are focused on: